Understanding Deeply · 11

Phase I design lab.

Change the world. Enroll a cohort. Watch the next dose change.

100% fictional data

v1.0 · Evidence checked 25 Oct 2026Educational simulations · not clinical dosing software

Search designs

Fictional worldTarget DLT 30%Participant limitSeed

Edit the fictional truth Known to the simulator, hidden from the design.

How this simulation works The rule, assumptions, and limits.

Fictional participant data Inspect or download the current sample.

Design map & sources Browse the full scope.

Study architectures and dose-selection algorithms answer different questions. SAD/MAD explore exposure; MTD designs target toxicity; dose optimization also weighs activity and tolerability.

“Specified rule” means the stated implementation. “Mechanism demo” is deliberately simplified; its results cannot rank the published methods. All outcomes, exposure units and participants are invented. Preprints are labeled separately.